Superman #41 (May 1946) features a story in which Superman gets seriously annoyed with Lois Lane. His inner monologue says it all:
“Whenever she goes out, I have to rescue her. She’s so used to it, she’s lost all sense of caution. It’s exhausting!”Clark Kent, “Clark Kent’s Bodyguard”, Superman #41, May 1946
But if that’s not enough, literally in the very next panel, Lois tumbles down an empty elevator shaft and Superman has to rescue her. This results in a humorous plot in which a dim-witted bodyguard is assigned to protect both Lois and Clark.